Middle East respiratory syndrome (MERS-CoV)

Middle East respiratory syndrome (MERS-CoV)

outbreak

Overview

Middle East respiratory syndrome coronavirus (MERS-CoV) is a virus transferred to humans from infected dromedary camels. It is a zoonotic virus, meaning it is transmitted between animals and people, and it is contractable through direct or indirect contact with infected animals. MERS-CoV has been identified in dromedaries in several countries in the Middle East, Africa and South Asia. In total, 27 countries have reported cases since 2012, leading to 858 known deaths due to the infection and related complications.

The origins of the virus are not fully understood but according to the analysis of different virus genomes it is believed that it may have originated in bats and later transmitted to camels.

Human-to-human transmission is possible, but only a few such transmissions have been found among family members living in the same household. In health care settings, however, human-to-human transmission appears to be more frequent.

 

 

Publications

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Middle East respiratory syndrome: global summary and assessment of risk
This global summary and assessment of risk for Middle East respiratory syndrome (MERS) reviews the global disease situation as of 5 January 2026. It replaces...
Strategic plan for coronavirus disease threat management: advancing integration, sustainability, and equity, 2025–2030

The WHO strategic plan for coronavirus disease threat management sets out the global framework for the sustained, integrated and evidence-based management...

Risk evaluation of circulating Middle East respiratory syndrome coronavirus (MERS-CoV) clades and lineages

Updated: 19 November 2025This document summarizes discussions during a Technical Advisory Group on Virus Evolution (TAG-VE) meeting held on 2 June 2025,...

Note: WHO has updated the guideline; find the latest version here: How to conduct a cohort study to assess the potential risk factors of Middle East...

Note: WHO has updated the guideline; find the latest version here: How to sample surfaces in health-care settings for Middle East respiratory syndrome...

Cross-sectional seroepidemiologic study of MERS-CoV infection in high risk populations in contact with dromedary camels

This study protocol outlines methods to collect data to measure the seroprevalence of cross-reactive antibodies to MERS-CoV in presumed high-risk human...

Cross-sectional seroepidemiologic study of MERS-CoV infection in high-risk populations in contact with dromedary camels

Representative serologic studies are designed to collect data to estimate prevalence of antibodies to a new pathogen in a population. This information...

Note: WHO has updated the guideline; find the latest version here: How to conduct a case-control study to assess the potential risk factors related to...